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In my experience the tolerable side effect of hyperactivity and stimming usually diminishes significantly or resolves completely by the 6 th month as the body up-regulates and down-regulates the appropriate metabolic sequences and enzymatic processes

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Biomarker-guided dosing (e.g., TF cysteine redox state, Prx cycling, 8-oxoG with repair indices) helps preserve beneficial transcriptional cues while preventing convergence onto nitrative and Fenton chemistry (Meng et al